The LaGrange community was established in the mid-1800s, between what would become Titusville and Mims. The LaGrange Church, organized in 1869, is the oldest Protestant church on the east coast of Florida, from New Smyrna to Key West.

The original church was built in what is now the northern section of LaGrange Cemetery. A two story log church was built in 1872, at the church’s current location southwest of the cemetery.